Abstract Background Methanol is regarded as a biorenewable platform feedstock because nearly all bioresources can be converted into methanol through syngas.Biological conversion of methanol using synthetic methylotrophs has thus gained worldwide attention.Results Herein, to endow Escherichia coli with the ability to utilize methanol, an click here
Phylogenetic and paleobotanical evidence for late Miocene diversification of the Tertiary subtropical lineage of ivies (Hedera L., Araliaceae)
Abstract Background Hedera (ivies) is one of the few temperate genera of the primarily tropical Asian Palmate group of the Araliaceae, which extends its range out of Asia to Europe and the Mediterranean basin.Phylogenetic and phylogeographic results suggested Asia as the center of origin and the western Mediterranean region as one of the secondary
GLP-1 Receptor Agonists: A Promising Therapy for Modern Lifestyle Diseases with Unforeseen Challenges
Modern lifestyle diseases remain a persistent challenge in healthcare.Currently, about 422 million people worldwide are affected by diabetes, while 1 in 8 people are living with obesity.The development of glucagon-like peptide 1 receptor agonists (GLP-1RAs) has marked a significant milestone in treating these conditions.Interest in GLP-1RAs has gro
A systematic review on clinical management of antipsychotic-induced sexual dysfunction in schizophrenia
INTRODUCTION: Sexual dysfunction frequently occurs in patients with schizophrenia under antipsychotic therapy, and the presence of sexual side effects may affect compliance.The aim of this study was to review and describe clinical findings relating to the appropriate management of such dysfunctions.MATERIAL AND METHODS: The research was carried out
Clustering Algorithm for Constructing Connected Graphs with Reverse Nearest Neighbors
The development of big data era makes the application of clustering algorithms more and more widespread, but most current clustering algorithms are sensitive to noisy data and cannot identify datasets with complex structures such as non-convex shapes.To address this problem, a clustering algorithm for constructing connected graph with reverse neare